Cefotaxime Side Effects – Causes and Effects


Category: Bacterial Infections

Drug Name: Cefotaxime

General Usage: To Treat Bacterial Infections

Brief Info about Cefotaxime in Drug:


This drug is sold under a brand name known as Claforan. Cefotaxime kills the bacteria in 3 stages-

  • Makes the cell wall weak
  • Rupture the cell wall
  • Kill the bacteria

Cefotaxime is used to cure infections caused by bacteria or to prevent bacterial infections before, after or during some surgeries.

Cefotaxime Side Effects Explained Better:

Adverse effect term associated with a medicine compels people to think what exactly they are? How they impose a risk on human health if it is used for a long period, if an extra dose of it is swallowed or if drug-drug, drug- food or drug- substance interactions take place. In a layman’s language, side effects are unpleasant or unwanted effects associated with a medicine besides its desired effects. A doctor always recommends a medicine that suits you best still unwanted effects are there.

There are different types of adverse effects that are divided on the basis of overdose, prolonged use of medicines, drug interactions besides frequent & infrequent side effects of a drug.

Frequent Cefotaxime Side Effects (Commonly Seen)-

If you have doubts about side effects, contact your doctor. Call your doctor for medical advice about adverse effects.

  • Nausea
  • Headache
  • Mild diarrhea
  • Vomiting

Infrequent Cefotaxime Side Effects (Professional Point of View)-

If you sense any of the following severe side effects, stop using this medicine and seek medical attention right off.

  • Symptoms of allergic reactions-
    • Hives
    • Rash
    • Tightness in the chest
    • Itching
    • Swelling of the mouth, lips, face, or tongue
    • Difficulty breathing
  • Decreased urination
  • Fever
  • Hoarseness
  • Bloody stools/diarrhea
  • Irregular heartbeat
  • Severe vomiting or nausea
  • Red, swollen, or blistered skin
  • Redness, pain, swelling, or at the injection site
  • White patches in mouth
  • Seizures
  • Severe diarrhea
  • Stomach pain/cramps
  • Unusual bleeding or bruising
  • Vaginal discharge or irritation
  • Yellowing of the skin and eyes
  • Unusual tiredness

Cefotaxime Overdose Side Effects (Require Immediate Medical Attention)-

Symptoms may include-

  • Muscle spasms
  • Seizures

Well, if you have an odd feeling after swallowing a huge quantity of this medicine, you must call your PCC (poison control board) or emergency room immediately.


Cefotaxime Drug Interaction Side Effects (Due to Reaction with Other drugs)-

Drug interaction occurs when the outcome of a specific medicine is altered when it is taken in combination with another medicine, alcohol, tobacco or with another food results in negative effects. Inform your doctor if you are having-

  • Heparin– the risk of its unpleasant effects, like risk of bleeding, may be increased by Cefotaxime
  • Aminoglycosides (such as- gentamicin)- the risk of kidney side effects may be increased

Remember: Prevention is better than cure!

Cefotaxime Prolonged Use Side Effects (When Used for Longer Periods)-

No adverse effects have been reported so far while using this medicine but the chances of their occurrences are always there. So, it is better you must check your progress at regular visits to make sure that Cefotaxime is working as it should be & doesn’t cause any adverse effects.