Demeclocycline – Information, Uses, Side Effects and Dosage


Drug Trade Name: Declomycin

Category: Tetracyclines

Generic Name: demeclocycline hydrochloride

Introduction and Quick Information About Demeclocycline:


Demeclocycline belongs to a group of medications called Tetracyclines. Declomycin is a brand name of Demeclocycline. This medicine is used to treat certain bacterial infections including those that cause acne.
This drug is also used in combination with some other medications to prevent amoeba infections in your intestines. Demeclocycline may also be taken for other health conditions as determined by your healthcare provider.
However, always consult your medical expert before taking this medication.

Is Demeclocycline Approved by U.S. FDA?

Demeclocycline was permitted or approved by U.S. FDA (Food and Drug Administration) on January 14, 1960, to treat and prevent certain bacterial infection.

Usage and Benefits of Demeclocycline:

This medicine is known as tetracycline antibiotic. Demeclocycline acts by interfering with the proteins production required by the bacteria to develop and allows your body’s defense system (white blood cells) to remove unhealthy bacteria. Demeclocycline treats certain bacterial infections. This drug may be taken in combination with some other drugs to prevent amoeba infections in your intestines. This medicine may also be consumed for other medical conditions as determined by your physician.

Demeclocycline Side Effects:

This medicine may lead to dizziness. This problem may get worse if you use Demeclocycline with certain medicines or alcohol. Patient should take this medicine with caution. You should avoid driving and performing other difficult tasks while consuming Demeclocycline for treating an infection. 

If you want to get best results, use this medicine on a regular basis. According to many specialists improper or misuse of medicine may lead to numerous side effects. Before using this drug you should consult your health care provider as it can lead to severe consequences if combined with certain drugs or consumed in large doses.

Possible adverse reactions of Demeclocycline:

  • Diarrhea
  • Dizziness
  • Indigestion
  • Loss of appetite
  • Headache
  • Sensitivity to sunlight
  • Nausea
  • Vomiting
  • Throat irritation
  • Blurred vision
  • Bloody stools
  • Dark urine
  • Decreased or increased urination
  • Increased thirst
  • Muscle weakness
  • Vaginal discharge or irritation
  • Weakness
  • Vision changes
  • Yellowing of the eyes or skin

It is not a complete list of side effects because patients can experience certain more as well. Seek immediate emergency medical attention or talk to your medical practitioner if you are experiencing any of them.

General Recommended Dosages of Demeclocycline:

Patients should take their drug dosages exactly as suggested by their medical practitioner. Avoid taking this drug in larger or smaller doses or for a longer period than recommended.  Patients must follow the important suggestions given in the prescription slip.


Take Demeclocycline on an empty stomach, at least after 2 hours or before 1 hour after your standard meal. The symptoms may get better before your disease is completely cured. This medicine is used for up to two days after the laboratory test to ensure that the bacteria has been inhibited.

The drug does not prevent any viral infection, such as the flu or common cold. The pateint should not share this medicine with anyone. Users should check with their doctor regularly while they are using Demeclocycline.

Store this drug away from heat, light, and moisture at a normal room temperature. However, before taking Demeclocycline you should consult your medical practitioner.

In case I Miss my Dose?

If you forget to take your regular dose of Demeclocyclin, use it as soon as you can. However, if it is the time to have your next scheduled dose, you should miss the skipped dose and follow your usual scheduled dose. Never think of taking a double dose to make up for the missed doses otherwise you might experience numerous unexpected symptoms.

Patients should call their medical expert if they forget to take their scheduled dosages of Demeclocyclin; talk to your medical expert and ask what do do in case you have skipped your regular dose of Demeclocyclin.

In case I Take Overdose?

You should be aware of adverse reactions that might occur if you more than recommended dosage of this drug. So, avoid consuming excess amount of any drug to prevent any unwanted side-effects.

In case you have consumed excess amount of this drug, you must contact your health care provider immediately. You must be very cautious about the recommended dosage of the drug as consuming more than that might cause serious consequences.

Drug Interactions of Demeclocycline:

Some medicines may interact with Demeclocycline. Patients should inform their physician if they are having any other medications along with Demeclocycline. Experts say that two or more drugs can negatively interact and lead to several serious health complications.

The following drugs can interact negatively with Demeclocycline:

  • Anticoagulants (warfarin), Acitretin, isotretinoin, digoxin, methoxyflurane, or methotrexate – The risk of their toxic side effects might be increased when used along with Demeclocycline
  • Hormonal birth control (birth control tablets) or Penicillins (amoxicillin) – Their efficiency might be reduced when used along with Demeclocycline

Ask your health care provider if Demeclocycline interacts with some other medication that you consume regularly. Visit your doctor before changing, stopping, or initiating any medicine.

 Life Style and Food Habits You Must Follow When on Demeclocycline:

Experts say that Demeclocycline can affect the growth of your child or lead to gray hair or yellow teeth.

Demeclocycline might lead to sunburn. Avoid tanning beds, sunlamps, or exposure to sun during treatment with Demeclocycline. Wear protective outfits or use an effective sunscreen before you step out of your home while using this medicine.

Before using this medication you should talk to your doctor.

How safe is Demeclocycline for Pregnant Women or Nursing Mothers?

Demeclocycline might be injurious to your developing fetus. Inform your doctor if you are expecting or planning to conceive while you are using this medication. This drug is under pregnancy category D by the U.S. FDA. Animal studies have revealed evidence of toxicity associated with the use of tetracyclines.

It is also not known whether Demeclocycline affects breast milk or not. This medication might not be suitable for a newborn baby. Do not use this medication if you are pregnant or if you are experiencing any unusual symptoms. Do not use this medicine without consulting your healthcare provider if you are a  breastfeeding mother.

Complications and Conditions Possible Due to Prolonged Use of Demeclocycline:

Prolonged use of Demeclocycline might cause numerous side effects which are actually injurious to your health and body. Doctors recommend consuming this medication  more than the prescribed duration. Extended use of any drug is actually harmful to your body. Sometimes long-term use of a drug might impose a risk on human life.

Use this medication as recommended by your medical healthcare professional or as directed on label of medication box. Prolonged use of any drug can make your body system reliant on it. In most of the cases, long-term use of drugs might also increase the risk of other health complications. So try to avoid using Demeclocycline longer than prescribed duration.

Better you talk to your physician & discuss everything about extended use of Demeclocycline, if you want to use it for a longer period.

Availability of Demeclocycline:

You can easily get Demeclocycline at any drug store. This medicine has been permitted by U.S. FDA, so it is easily available at any government approved medical stores.

However, it is advised to consult your doctor before using this medicine.