Amid the race to develop a Covid-19 vaccine, Novavax, a biotech company\u2019s COVID-19 vaccine study generated a promising immune response in an early-stage clinical trial in results unveiled recently, reports The Wall Street Journal.<\/p>\n
The company has never brought a vaccine to market in its 33-year history but its reputation got a boost in July when the biotechnology company received a $1.6 billion grant from the US government’s Operation Warp Speed to have 100 million doses ready by early 2021.<\/p>\n
Novavax Inc.\u2019s experimental vaccine for Covid-19 showed signs of promise in an early-stage study, becoming the latest shol;78=-09651qaapity t to clear initial hurdles in the race to protect against the coronavirus. The two-injection regimen when administered concurrently with Novavax\u2019s immune-boosting technology dubbed Matrix-M generated antibody responses that were four times higher than those seen in people who had recovered from the disease. The vaccine also brought about responses from T-cells, which help the immune system fight off infection.<\/p>\n
The phase one trial included 131 healthy participants between the ages of 18 and 59 at two sites in Australia.<\/p>\n
Novavax, of Maryland, said the vaccine was “well-tolerated and had a reassuring safety profile” and provoked an immune response with higher levels of antibodies in people who received the vaccine than in people who had recovered from coronavirus. Scientists mixed stable, a prefusion protein with a compound called an adjuvant to improve the performance of the vaccine.<\/p>\n
Novavax said the vaccine was well tolerated with no serious adverse events reported. Some participants reported mild side effects such as fatigue, muscle aches, and headaches lasting a maximum of two days.<\/p>\n
“The Phase 1 data demonstrate that NVX-CoV2373 with our Matrix-M adjuvant is a well-tolerated COVID-19 vaccine with a robust immunogenicity profile,” Gregory Glenn, president for research and development at Novavax, said in a statement.<\/p>\n
Novovax (NVAX) is slated to start a 30,000-person final-stage study in the fall which will test whether the immune responses triggered by the vaccine safely protect people from the coronavirus.<\/p>\n
Novavax is partnered with another Maryland-based company, Emergent Biosolutions Inc. to manufacture its vaccine.<\/p>\n","protected":false},"excerpt":{"rendered":"
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