{"id":18937,"date":"2017-12-09T19:00:01","date_gmt":"2017-12-09T13:30:01","guid":{"rendered":"https:\/\/zovon.com\/?p=18937"},"modified":"2018-07-30T14:40:52","modified_gmt":"2018-07-30T09:10:52","slug":"depakote","status":"publish","type":"post","link":"https:\/\/zovon.com\/?p=18937","title":{"rendered":"Depakote &#8211; Information, Uses, Side Effects and Dosage"},"content":{"rendered":"<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong>Drug trade name-<\/strong>Depakote<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong>Category-<\/strong> anticonvulsant<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong>Generic name-<\/strong> <em>Divalproex Sodium<\/em><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong>Group-<\/strong> pharmaceuticals<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong>Introduction and Quick Information:<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">Depakote contains a compound of valproic acid and sodium valproate in a coated form. This medicine used in the treatment of various types of seizure disorders and manic episodes of bipolar disorder. In certain cases, it is also used in the treatment of the major depressive disorder and recommend for long-term treatment for both depressive and manic of bipolar disorder. In United States, it is widely prescribed or recommended for the treatment of a migraine headache, epilepsy and chronic pain associated with neuropathy. Depakote comes under the chemical name of sodium hydrogen.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong>Is Depakote approved by FDA?<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">Valproic acid and its derivative Divalproex comes under the brand name called Depakote. Both chemicals were approved by United States Food and Drug Administration (FDA). \u00a0The FDA has approved both these chemicals in different years as the valproic acid was approved in February 1978 and the later approved in March 1983 by FDA. This medicine is being sold worldwide under different brand names.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong>Usage and Benefits of Depakote<\/strong>:<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">Depakote is used in the treatment of acute manic episodes associated with the associated bipolar disorder.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">In certain health condition, this medicine is taken alone or with seizure medications which are generally prescribed to treat seizure disorder in adults and children (older than 10 years).<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">Depakote works to improve concentrations of the neurotransmitter gamma-aminobutyric acid (well known as GABA) in the brain which further helps to prevent seizures from occurring.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">Depakote is also used to reduce the effects of manic episodes associated with bipolar disorder. Apart from this, it is also prescribed for preventing migraine headache, but it is not used to treat a migraine headache.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong>Side Effects of Depakote<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">Seek for medical emergency or attention, if you experience any of the below mentioned health condition while using Depakote-<\/span><\/p>\n<ul style=\"text-align: justify;\">\n<li><span style=\"font-size: 12pt;\">hallucinations (seeing things that aren&#8217;t there);<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">urinating less than usual<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">easy bruising or bleeding, blood in your urine<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">double vision or back-and-forth movements of the eyes<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">body aches, fever, sore throat, chills, flu symptoms<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">lack of coordination, extreme drowsiness<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">unexplained weakness with vomiting and confusion or fainting<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">headache with a severe blistering, peeling and red skin rash<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">enlarged breasts<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">weight changes<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">mild drowsiness or weakness<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">changes in your menstrual periods<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">anxiety, depression, or other emotional changes<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">upset stomach, constipation, diarrhea<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">hair loss<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">vision changes<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">unpleasant taste in your mouth<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">facial swelling<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">hypothermia<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">severe stomach pain<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">unexplained lethargy<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">loss appetite<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">vomiting<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">fever<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">jaundice<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">dizziness<\/span><\/li>\n<\/ul>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">These health conditions are medically known as side effects of Depakote which occur due to various reasons and sometimes due to overdose. Immediate medical help and attention are recommended by the doctors to avoid the minor\/serious health damage caused due to side effects.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong>General Recommended Dosages of Depakote:<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">Recommended dosages for seizure treatment is initiated with 10 to 15 mg\/kg\/day and added by 5 to10 mg\/kg\/day per week to get quick and desired response. However, dosage amount is not same for every patient as dosage amount depends on patient\u2019s age, weight and health condition.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">Recommended dosage for acute mania associated with bipolar disorder- treatment is initiated with 750 mg every day. Further dose should be increased rapidly to get the maximum health benefits and effects. Maximum dose of Depakote is 60 mg\/kg\/day.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">Recommended dosages for the prevention of migraines- treatment is started with 250 gm twice in a day. Further dose should be increased slowly to get maximum health benefits and effects; maximum dose of Depakote is 60 mg\/kg\/day.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">These dosages can only be prescribed by your doctor or health care provider. Before taking Depakote, you need to undergo some medical tests to make sure that you are not having any serious health conditions. You cannot take this medicine if you have some serious health complications as it can worsen them.<br \/>\n<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong>In Case I Miss a Dose?<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">Missed dose consequences are not known. Take the missed dose as soon as you remember it. Skip the missed dose if it is time for next dose. Inform your doctor about the missed dose and do not try to take a double dose to make up for the missed one.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong>In Case I Take Overdose?<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">Overdose of Depakote can have several health complications which can worsen your disease or disorder condition for which you are taking this medicine.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">Overdose symptoms may include loss of consciousness, shallow breathing, drowsiness or sleepiness, weak pulse. Ask your doctor for further information on overdose symptoms.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong>Drug Interactions of Depakote<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">Drug interactions could have some serious side effects to the body hence it is recommended to get full information of Depakote interaction with other drugs before using this medicine. Here we have some drugs enlisted which interact with Depakote and could lead to fatal effects on the body.<\/span><\/p>\n<ul style=\"text-align: justify;\">\n<li><span style=\"font-size: 12pt;\">Carbamazepine<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Lamotrigine<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Rifampin<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Phenobarbital<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Diazepam<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Clonazepam<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Phenytoin<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Felbamate<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Topiramate<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Zidovudine<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Ethosuximide<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Primidone<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Aspirin<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Warfarin<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Carbapenem antibiotics such as ertapenem, imipenem or meropenem<\/span><\/li>\n<\/ul>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong>Life Style and Food habits one must follow When on Depakote:<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">Almost every medicine has certain food restrictions and Depakote has too. You can ask your doctor for the list of foods which you should avoid during the treatment. Your doctor will provide you complete information of what you should do and how to go about it.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">Drinking alcohol or smoking in an excessive manner can increase the adverse effects. There are some other medical conditions which you should tell your doctors before starting with this drug. Do inform your doctor if you have any of these health issues-<\/span><\/p>\n<ul style=\"text-align: justify;\">\n<li><span style=\"font-size: 12pt;\">HIV or CMV (cytomegalovirus) infection<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Bleeding or blood clotting disorder<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Urea cycle disorder<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Brain disorder, head injury or coma<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Family history of infant deaths with unknown cause<\/span><\/li>\n<\/ul>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">You need to give a minor medical test to make sure that your body and health condition are suitable for this treatment.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong>How safe is Depakote for Pregnant Women or Nursing Mothers?<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">One should never use any drug during pregnancy or nursing a baby. When you are in such condition, inform your doctor as it could have some severe effects to the body. Several studies have shown that Depakote can harm unborn babies. Do not use this medicine until your doctor does not prescribe it. You should not use this medicine if you are breast-feeding a baby.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong>Complication and Conditions Possible due to Prolonged Use of Depakote<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">Although depakote does not have any habit-forming capabilities however it may harm your health if you use this medicine longer than recommended. Prolonged use of Depakote can lead to certain health issues and complication which you can know more about from your healthcare provider. Ask your doctor for possible complication and condition of prolonged use of this anticonvulsant.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong>Availability of the Drug Depakote<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">Depakote is a FDA approved anticonvulsant drug and available at only government and FDA approved drug stores. Remember this is a prescription medicine and you cannot buy this medication without a doctor\u2019s prescription.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Drug trade name-Depakote Category- anticonvulsant Generic name- Divalproex Sodium Group- pharmaceuticals Introduction and Quick Information: Depakote contains a compound of valproic acid and sodium valproate in a coated form. This medicine used in the treatment of various types of seizure disorders and manic episodes of bipolar disorder. In certain cases, it is also used in [&hellip;]<\/p>\n","protected":false},"author":19,"featured_media":33749,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"tdm_status":"","tdm_grid_status":"","footnotes":""},"categories":[18940],"tags":[29601,29602],"class_list":{"0":"post-18937","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-know-your-drug","8":"tag-depakote","9":"tag-depakote-drugs"},"_links":{"self":[{"href":"https:\/\/zovon.com\/index.php?rest_route=\/wp\/v2\/posts\/18937","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zovon.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zovon.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zovon.com\/index.php?rest_route=\/wp\/v2\/users\/19"}],"replies":[{"embeddable":true,"href":"https:\/\/zovon.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=18937"}],"version-history":[{"count":0,"href":"https:\/\/zovon.com\/index.php?rest_route=\/wp\/v2\/posts\/18937\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/zovon.com\/index.php?rest_route=\/wp\/v2\/media\/33749"}],"wp:attachment":[{"href":"https:\/\/zovon.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=18937"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zovon.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=18937"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zovon.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=18937"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}