{"id":18855,"date":"2017-12-09T04:00:10","date_gmt":"2017-12-08T22:30:10","guid":{"rendered":"https:\/\/zovon.com\/?p=18855"},"modified":"2018-07-30T15:06:07","modified_gmt":"2018-07-30T09:36:07","slug":"enablex","status":"publish","type":"post","link":"https:\/\/zovon.com\/?p=18855","title":{"rendered":"Enablex \u2013 Information, Uses, Side effects and Dosage"},"content":{"rendered":"<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong>Drug Trade Name:\u00a0<\/strong>Enablex<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong>Category:\u00a0<\/strong>Anticholinergics or Antimuscarinics<\/span><\/p>\n<p style=\"text-align: justify;\"><strong style=\"font-size: 12pt;\">Generic name: <\/strong><span style=\"font-size: 12pt;\">darifenacin<\/span><strong style=\"font-size: 12pt;\">\u00a0<\/strong>h<span style=\"font-size: 12pt;\">ydrobromide<\/span><strong style=\"font-size: 12pt;\"><span style=\"font-size: 12pt;\">\u00a0<\/span> \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0\u00a0<\/strong><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong>Introduction and Quick Information:<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">Enablex is an extended-release pill, which has 15 mg or 7.5 mg darifenacin hydrobromide as an active ingredient. Darifenacin is one of the powerful muscarinic receptor antagonists. This medication works by actually clogging the M<sub>3<\/sub>\u00a0muscarinic acetylcholine receptor, the chief triggering factor that contributes to bladder\u00a0muscle contractions. It thereby assists in treating the symptoms of an overactive bladder like incontinence (urine leakage) and urgent or frequent urination. However, it should not be used in patients with complaints of urinary retention.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong>Is Enablex<\/strong> <strong>Approved by FDA?<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-family: verdana, geneva, sans-serif; font-size: 12pt;\">U.S. FDA (Food and Drug Administration) has approved this drug for an overactive bladder.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong>Usage and Benefits of Enablex:<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">Enablex is indicated in the treatment of an overactive bladder. An overactive bladder is characterized by a sudden and frequent urge to urinate. This is a result of stimulation of muscarinic receptors of the bladder, which lead to bladder contraction. Sometimes, this can lead to a sudden loss of bladder control and an involuntary urination (urge incontinence). <\/span><\/p>\n<p><span style=\"font-size: 12pt;\">By blocking muscarinic receptors, Enablex relieves the symptoms of an overactive bladder.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong>Side Effects of Enablex:<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">Some possible Enablex side effects are:<\/span><\/p>\n<ul style=\"text-align: justify;\">\n<li><span style=\"font-size: 12pt;\">dry, hot skin<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">burning or pain while urinating<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">bloody or cloudy urine<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">lower back or side pain<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">extreme thirst<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">blurred vision<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">severe constipation or stomach pain<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">urinating not at all or less than usual<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">excessive dry mouth<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">diarrhea<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">mild constipation<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">mild stomach pain<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">dry eyes<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">too much headache<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">an excessive sore throat<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">nausea<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">uncontrollable dizziness<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">fever<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">body aches and weakness<\/span><\/li>\n<\/ul>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">Seek medical help if you experience these side-effects.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong>General Recommended Dosages of Enablex:<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">This medicine is available in tablet form. You just need to take it once a day.\u00a0<\/span><span style=\"font-size: 12pt;\">You can use Enablex drug without or with your meals. Y<\/span><span style=\"font-size: 12pt;\">ou have to swallow it as a whole with liquids. Don\u2019t try to chew, break, or crush the tablets.\u00a0<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">In case of query related to dosage prescribed to you, talk to your doctor, nurse, or pharmacist. Do not stop taking the drug without first discussing it with your healthcare provider.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">Consult your doctor if you develop signs of allergy, such as hives, rash, trouble breathing, etc. Also, inform your doctor if you have:<\/span><\/p>\n<ul style=\"text-align: justify;\">\n<li><span style=\"font-size: 12pt;\">uncontrolled or untreated narrow-angle glaucoma<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">a stomach disorder<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">if you are unable to urinate<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">ulcerative colitis<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">liver disease<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">glaucoma<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">a blockage in your intestines or stomach<\/span><\/li>\n<\/ul>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong>In Case I Miss the Dose?<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">Take the missed-one dose the moment you remember about it. However, if it\u2019s almost time to have the next scheduled dose, then just miss the skipped dose and have the next scheduled dose.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong>In Case I Take Overdose?<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">Some of the common symptoms of an overdose of Enablex are stomach pain or severe constipation, urinating not at all or less than normal or extreme weakness. In case of overdose, adequate supportive care is needed. So consult your doctor as soon as possible.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong>Drug Interactions of Enablex:<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">Consumption of two separate drugs together can cause some deleterious effects. Some common drugs that can interact with Enablex are:<\/span><\/p>\n<ul style=\"text-align: justify;\">\n<li><span style=\"font-size: 12pt;\">other anticholinergic drugs like oxybutynin (Oxytrol, Ditropan), flavoxate (Urispas), solifenacin (Vesicare) or tolterodine (Detrol)<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">thioridazine (Mellaril)<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">flecainide (Tambocor)<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">glycopyrrolate (Robinul)<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">mepenzolate (Cantil)<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">antifungal medication like ketoconazole (Nizoral) or itraconazole(Sporanox)<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">an antibiotic like clarithromycin (Biaxin), troleandomycin (Tao) or erythromycin (E-Mycin, E.E.S., Erythrocin, Ery-Tab)<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">anti-retroviral drugs like ritonavir (Norvir) or nelfinavir (Viracept)<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">benztropine (Cogentin), atropine (Donnatal, etc), methscopolamine (Pamine), dimenhydrinate (Dramamine), or scopolamine (Transderm-Scop);<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">irritable bowel drugs like propantheline (Pro-Banthine), dicyclomine (Bentyl), hyoscyamine (Cystospaz, Anaspaz, Levsin, etc)<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">bronchodilators like tiotropium (Spiriva) or ipratropium (Atrovent)<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">antidepressants like amitriptyline (Etrafon, Elavil), fluvoxamine (Luvox), fluoxetine (Prozac), desipramine (Norpramin), clomipramine (Anafranil), imipramine (Tofranil, Janimine), doxepin (Sinequan), paroxetine (Paxil), nortriptyline (Pamelor), and others.<\/span><\/li>\n<\/ul>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong>Lifestyle and Food Habits You Must Follow When On Enablex:<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 16px;\">The interaction of Enablex with alcohol is not known. Hence, consult your doctor before consuming alcohol when on Enablex.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong>How Safe Is Enablex for Pregnant Women or Nursing Mothers<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">Research has shown evidence of fetal risk on the administration of this drug. Hence, Enablex should be administered during pregnancy\u00a0only if the benefit outweighs the risk to the fetus.<\/span><\/p>\n<p><span style=\"font-size: 12pt;\">The drug is excreted in the human milk or not is unknown. Hence, the safe use of this drug in nursing mother cannot be assured.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong>Complications and Conditions Possible Due to Prolonged Use of Enablex:<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">The addiction liability of this drug is not known. However, sudden stoppage of the drug is not recommended.\u00a0<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong>Availability of Enablex:<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 16px;\">Because of some serious side-effects associated with the drug, Enablex is available on a doctor&#8217;s prescription only.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Drug Trade Name:\u00a0Enablex Category:\u00a0Anticholinergics or Antimuscarinics Generic name: darifenacin\u00a0hydrobromide\u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0\u00a0 Introduction and Quick Information: Enablex is an extended-release pill, which has 15 mg or 7.5 mg darifenacin hydrobromide as an [&hellip;]<\/p>\n","protected":false},"author":19,"featured_media":33762,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"tdm_status":"","tdm_grid_status":"","footnotes":""},"categories":[18940],"tags":[29612,29613],"class_list":["post-18855","post","type-post","status-publish","format-standard","has-post-thumbnail","category-know-your-drug","tag-enablex","tag-enablex-drug"],"_links":{"self":[{"href":"https:\/\/zovon.com\/index.php?rest_route=\/wp\/v2\/posts\/18855","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zovon.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zovon.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zovon.com\/index.php?rest_route=\/wp\/v2\/users\/19"}],"replies":[{"embeddable":true,"href":"https:\/\/zovon.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=18855"}],"version-history":[{"count":0,"href":"https:\/\/zovon.com\/index.php?rest_route=\/wp\/v2\/posts\/18855\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/zovon.com\/index.php?rest_route=\/wp\/v2\/media\/33762"}],"wp:attachment":[{"href":"https:\/\/zovon.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=18855"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zovon.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=18855"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zovon.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=18855"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}