{"id":18273,"date":"2017-11-29T13:04:17","date_gmt":"2017-11-29T07:34:17","guid":{"rendered":"https:\/\/zovon.com\/?p=18273"},"modified":"2018-07-31T10:36:47","modified_gmt":"2018-07-31T05:06:47","slug":"cabazitaxel","status":"publish","type":"post","link":"https:\/\/zovon.com\/?p=18273","title":{"rendered":"Cabazitaxel \u2013 Information, Uses and Side Effects"},"content":{"rendered":"<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong>Drug Trade Name:<\/strong><strong>\u00a0<\/strong>Jevtana<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong>Category: <\/strong>Cancer &amp; Oncology (microtubule inhibitor)<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong>Generic Name: <\/strong>cabazitaxel<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong>Introduction and Quick Information:<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">Cabazitaxel is used to treat prostate cancer in some people.\u00a0 This medicine is used in combination with prednisone.\u00a0<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">Cabazitaxel acts by\u00a0suppressing microtubule function, which is essential for normal mitotic activity. Cabazitaxel is an antineoplastic agent.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong>Is It Approved by FDA?<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">Cabazitaxel was approved in 2010 June 17 by the U.S. FDA (U.S. Food and Drug Administration).<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong>Usage and Benefits of Cabazitaxel:<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">Cabazitaxel is used to:<\/span><\/p>\n<ul style=\"text-align: justify;\">\n<li><span style=\"font-size: 12pt;\">Treat prostate cancer<\/span><\/li>\n<li><span style=\"font-size: 16px;\">Suppresses the activity of microtubules, thereby, restricting mitotic cell division<\/span><\/li>\n<\/ul>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">Cabazitaxel can also be used for purposes others than the ones listed above. You can get more information about other uses of this medicine by talking to your doctor.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong>Cabazitaxel Side Effects:<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">From over-the-counter (OTC) medications like minerals and herbal products to prescription medications, it is impossible to find a drug without side effects. Just like any other anti-cancer drug,\u00a0Cabazitaxel also has a number of side effects.\u00a0<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong>Frequent Cabazitaxel Side Effects:<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">If any of these effects persist\u00a0for a long time, you should notify your doctor at once to escape from its deleterious effects. Its common side effects are listed below:<\/span><\/p>\n<ul style=\"text-align: justify;\">\n<li><span style=\"font-size: 12pt;\">Back pain<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Fatigue<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Hair loss<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Dizziness<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Indigestion<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Numbness<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Diarrhea<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Joint pain<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Redness at the injection site<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Mild pain<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Constipation<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Stomach pain<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Swelling<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Mild weight loss<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Vomiting<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Nausea<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Muscle spasms<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Tiredness or weakness<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Loss of appetite<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Burning or tingling sensation in the feet and hands or taste-related changes<\/span><\/li>\n<\/ul>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong>Infrequent Cabazitaxel Side Effects:<\/strong><\/span><\/p>\n<ul style=\"text-align: justify;\">\n<li><span style=\"font-size: 12pt;\">Symptoms of allergic reactions:<\/span>\n<ul>\n<li><span style=\"font-size: 12pt;\">Itching<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Hives<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Swelling of the lips, mouth, face, or tongue<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Rash<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Difficulty breathing<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Tightness in the chest<\/span><\/li>\n<\/ul>\n<\/li>\n<li><span style=\"font-size: 12pt;\">Blood in the urine<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Headache<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Diarrhea<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Stomach pain<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Slow, fast, or erratic heartbeat<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Fainting<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Persistent or severe nausea<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Shortness of breath<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Persistent or severe dizziness<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Vomiting<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Mouth inflammation or sores<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Persistent or severe tiredness or weakness<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Persistent or severe weight loss<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Symptoms of bleeding in the brain:<\/span>\n<ul>\n<li><span style=\"font-size: 12pt;\">Confusion<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Slurred speech<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">One-sided weakness<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Vision problems<\/span><\/li>\n<\/ul>\n<\/li>\n<li><span style=\"font-size: 12pt;\">Symptoms of dehydration:<\/span>\n<ul>\n<li><span style=\"font-size: 12pt;\">Fast or erratic heartbeat<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Very dry skin<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Mouth, or eyes<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Increased thirst<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Weakness<\/span><\/li>\n<\/ul>\n<\/li>\n<li><span style=\"font-size: 12pt;\">Symptoms of infection:<\/span>\n<ul>\n<li><span style=\"font-size: 12pt;\">Sore throat<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Muscle aches<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Chills<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Cough<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Swollen lymph glands<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Fever<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Painful or increased urination<\/span><\/li>\n<\/ul>\n<\/li>\n<li><span style=\"font-size: 12pt;\">Symptoms of kidney problems:<\/span>\n<ul>\n<li><span style=\"font-size: 12pt;\">Swelling of the ankles, face, hands, feet or other parts of the body<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Decreased amount of urine produced<\/span><\/li>\n<\/ul>\n<\/li>\n<li><span style=\"font-size: 12pt;\">Unusual bleeding or bruising<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Wheezing<\/span><\/li>\n<\/ul>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">As you notice the\u00a0<\/span>above-listed<span style=\"font-size: 12pt;\"> side effects, you must immediately consult your doctor to get medical assistance at the earliest.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong>General Recommended Dosages of Cabazitaxel:<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">Nowadays,\u00a0<\/span>people, especially in metropolitan cities, <span style=\"font-size: 12pt;\">flinch from going to a doctor due to easy accessibility to the internet &amp; try to diagnose a disease\/syndrome\/illness on their own by getting information on the net. It is good to read information related to a disease on the internet, but remember that it is your medical healthcare provider who can better guide you for how to take a particular medicine by defining its amount, strength\/power &amp; dosage time. So, always follow your doctor\u2019s advice for proper dosing instructions.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">When you a buy a medicine, it usually comes with a leaflet that guides you on how to take a particular medicine. If you still have confusion about the same, you must talk to your doctor.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">Cabazitaxel is administered as an injection at hospitals, doctor\u2019s office or clinic. It is taken along with other drugs like prednisone. It is also mandatory to have prednisone as prescribed by your doctor. You must let your doctor know if you have forgotten to take a dose of prednisone or if you have not taken the same as prescribed.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong>In Case I Miss the Dose?<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">Well, if you have forgotten to have the medicine on time, no need to be freaked out because this situation can be easily handled by taking the missing dose the moment you remember. If it is a time to have the next scheduled dose, better you skip the missed dose rather than having a double dose of this medicine. However, if you have missed more than one dose, you should talk to your doctor to stamp out this problem.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong>In Case I Take the Overdose?<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">If you have taken an overdose of Cabazitaxel, you should rush to\u00a0<\/span><span style=\"font-size: 12pt;\">the nearby hospital before the condition worsens.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">Symptoms may include:<\/span><\/p>\n<ul style=\"text-align: justify;\">\n<li><span style=\"font-size: 12pt;\">Sore throat<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Chills<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Persistent or severe nausea<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Fever<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Unusual bleeding or bruising<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Vomiting<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Cough<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Diarrhea<\/span><\/li>\n<\/ul>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong>Drug Interactions of Cabazitaxel:<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">It has been observed that some people use more than one drug for a specific disease\/illness or for different disorders. Many of these combinations are likely to interact negatively. Drugs interact with other drugs, whether these are prescription or over the counter medications.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">Let your healthcare professional know if you are having some vitamins, herbal or minerals products, drugs that have been prescribed to you by some\u00a0other doctor etc.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">Here are some medicines that may interact with Cabazitaxel-<\/span><\/p>\n<ul>\n<li><span style=\"font-size: 12pt;\">Azole antifungals like:<\/span>\n<ul>\n<li><span style=\"font-size: 12pt;\">Voriconazole<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Itraconazole<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Ketoconazole<\/span><\/li>\n<\/ul>\n<\/li>\n<li><span style=\"font-size: 12pt;\">Macrolide antibiotics like:<\/span>\n<ul>\n<li><span style=\"font-size: 12pt;\">Clarithromycin<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Erythromycin<\/span><\/li>\n<\/ul>\n<\/li>\n<li><span style=\"font-size: 12pt;\">HIV protease inhibitors like:<\/span>\n<ul>\n<li><span style=\"font-size: 12pt;\">Atazanavir<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Ritonavir<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Indinavir<\/span><\/li>\n<\/ul>\n<\/li>\n<li><span style=\"font-size: 12pt;\">Nefazodone<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Telithromycin<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Nifedipine<\/span><\/li>\n<\/ul>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">All these above-listed medicines increase the risk of Cabazitaxel&#8217;s side effects<\/span><\/p>\n<ul style=\"text-align: justify;\">\n<li><span style=\"font-size: 12pt;\">Rifamycin, such as:<\/span>\n<ul>\n<li><span style=\"font-size: 12pt;\">Rifapentine<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Rifabutin<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Rifampin<\/span><\/li>\n<\/ul>\n<\/li>\n<li><span style=\"font-size: 12pt;\">Phenytoin<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Carbamazepine<\/span><\/li>\n<li><span style=\"font-size: 12pt;\">Phenobarbital<\/span><\/li>\n<\/ul>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">These drugs may reduce Cabazitaxel&#8217;s effectiveness.<\/span><\/p>\n<ul style=\"text-align: justify;\">\n<li><span style=\"font-size: 12pt;\">Palifermin<\/span><\/li>\n<\/ul>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">It may increase the risk of inflammation or mouth sores.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong>Note:<\/strong> This is not the complete list of medicines that might interact with Cabazitaxel.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong>Lifestyle and Food Habits You Must Follow When on Cabazitaxel:<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">It has been seen that Cabazitaxel decreases the number of platelets (clot-forming cells) in the blood. So, you should restrict those activities that may cause injury or bruising. \u00a0Let your doctor know if you have unusual bleeding or bruising. Inform your medical healthcare provider know if you have tarry, bloody or dark stool. This medicine reduces the ability of our body to fight off infection. You should avoid contact with people, who have infections or cold. Visit your doctor if you observe symptoms like sore\u00a0<\/span><span style=\"font-size: 12pt;\">throat, chills, fever or rash.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">Don\u2019t forget to inform your doctor about nonprescription medications, vitamins, minerals, dietary supplements as well as prescription drugs that you\u00a0are consuming, or if you have a weak immune system or low white blood cell count.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong>How Safe is Cabazitaxel for Pregnant Women or Nursing Mothers?<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">This medicine kept\u00a0under the pregnancy category &#8220;D.&#8221; Cabazitaxel may cause harm to the unborn baby. You should avoid this medicine when you are pregnant. Do not think of getting pregnant while using this medicine. If you believe that you are pregnant, let your medical healthcare professional know about the same without delay.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">It is still unknown whether Cabazitaxel is present in the human breast milk or not. Well, as a preventive measure, you must stop breastfeeding while having this drug.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong>Complications and Conditions Possible Due to Prolonged Use of Cabazitaxel:<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">If a medical healthcare professional recommends a medicine for the lifetime, it might create a problem by affecting the bodily functions. So, you must report to your medical healthcare provider about any new signs noticed by you while having this medicine. You may be required to change the drug or have a dose adjustment.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong>Availability of Cabazitaxel:<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">You can buy Cabazitaxel from any of the local health centers authorized by the U.S. Food &amp; Drug Administration, other medical centers or government recognized hospitals.\u00a0 This medicine is available only on prescription.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong>\u00a0<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong>\u00a0<\/strong><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Drug Trade Name:\u00a0Jevtana Category: Cancer &amp; Oncology (microtubule inhibitor) Generic Name: cabazitaxel Introduction and Quick Information: Cabazitaxel is used to treat prostate cancer in some people.\u00a0 This medicine is used in combination with prednisone.\u00a0 Cabazitaxel acts by\u00a0suppressing microtubule function, which is essential for normal mitotic activity. Cabazitaxel is an antineoplastic agent. Is It Approved by [&hellip;]<\/p>\n","protected":false},"author":19,"featured_media":33806,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"tdm_status":"","tdm_grid_status":"","footnotes":""},"categories":[18940],"tags":[],"class_list":{"0":"post-18273","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-know-your-drug"},"_links":{"self":[{"href":"https:\/\/zovon.com\/index.php?rest_route=\/wp\/v2\/posts\/18273","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zovon.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zovon.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zovon.com\/index.php?rest_route=\/wp\/v2\/users\/19"}],"replies":[{"embeddable":true,"href":"https:\/\/zovon.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=18273"}],"version-history":[{"count":0,"href":"https:\/\/zovon.com\/index.php?rest_route=\/wp\/v2\/posts\/18273\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/zovon.com\/index.php?rest_route=\/wp\/v2\/media\/33806"}],"wp:attachment":[{"href":"https:\/\/zovon.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=18273"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zovon.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=18273"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zovon.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=18273"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}