{"id":17733,"date":"2017-11-23T15:00:29","date_gmt":"2017-11-23T09:30:29","guid":{"rendered":"https:\/\/zovon.com\/?p=17733"},"modified":"2018-06-21T17:15:01","modified_gmt":"2018-06-21T11:45:01","slug":"first-2-drug-hiv-regimen-approved-fda","status":"publish","type":"post","link":"https:\/\/zovon.com\/?p=17733","title":{"rendered":"First 2-drug HIV regimen approved by FDA"},"content":{"rendered":"<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">The first two-drug program has been approved by U.S. Food and Drug Administration (FDA) for the treatment of AIDS-causing virus. This drug plan aimed at easing up the side effects of the standard treatment processes that involve three or more drugs, especially in case of long-term patients. <\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">The two-drug treatment is known as Juluca. This comprises a fixed dose of a combination of two drugs, viz., viz. dolutegravir and rilpivirine, that had been already approved by FDA. This treatment is available to patients, who are on a stable treatment plan for at least six months.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">Juluca is manufactured by ViiV Healthcare, whose major shareholder is GlaxoSmithKline (GSK) with Pfizer and Shionogi being the minor shareholders. GSK has a traditional triple therapy for the treatment of HIV and dolutegravir is a part of it. <\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">The approval of Juluca has put GSK a rank higher to its competitor, Gilead Sciences in the 2-drug combination market for HIV treatment. However, there are speculations that Juluca will cover the market a bit slower, because the drug rilpivirine has some limitations as it can only be taken with the meal at the same time every day.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">GSK is now working on a new two-drug combination in which the rilpivirine can be replaced with a drug called 3TC. It is estimated that this combination will be in the market by the second half of 2019, but only after successful clinical trials.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong>Source:foxnews.com<\/strong><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The first two-drug program has been approved by U.S. Food and Drug Administration (FDA) for the treatment of AIDS-causing virus. This drug plan aimed at easing up the side effects of the standard treatment processes that involve three or more drugs, especially in case of long-term patients. The two-drug treatment is known as Juluca. This [&hellip;]<\/p>\n","protected":false},"author":18,"featured_media":30748,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"tdm_status":"","tdm_grid_status":"","footnotes":""},"categories":[12661],"tags":[33325,236,181],"class_list":["post-17733","post","type-post","status-publish","format-standard","has-post-thumbnail","category-popular-topics","tag-aids-causing-virus","tag-drug","tag-hiv"],"_links":{"self":[{"href":"https:\/\/zovon.com\/index.php?rest_route=\/wp\/v2\/posts\/17733","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zovon.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zovon.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zovon.com\/index.php?rest_route=\/wp\/v2\/users\/18"}],"replies":[{"embeddable":true,"href":"https:\/\/zovon.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=17733"}],"version-history":[{"count":0,"href":"https:\/\/zovon.com\/index.php?rest_route=\/wp\/v2\/posts\/17733\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/zovon.com\/index.php?rest_route=\/wp\/v2\/media\/30748"}],"wp:attachment":[{"href":"https:\/\/zovon.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=17733"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zovon.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=17733"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zovon.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=17733"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}