Resveratrol Sources, Benefits, Side Effects & FAQs

resveratrol sources benefits side effects faqs

Resveratrol is a form of polyphenol that acts as an antioxidant and helps in the prevention and recovery of various internal cellular damages in the body. Resveratrol is produced in the skin of grapes as a defense against toxins. It is considered to be the compound that helps in providing the longevity to the animals but does not have the same role in human beings. Though, it protects the humans from developing heart disease and insulin resistance. Its major sources are plants including different kind of berries, seeds, and nuts.


Resveratrol is present in two forms in nature i.e. cis and trans. The trans form is found to be available in active form. The cis-resveratrol is not available as an active compound but has a role in gene transcription as an antioxidant.


Resveratrol is a derivative of stilbene and produced by the plants in the presence of stilbene synthase enzyme. The amount of resveratrol produced within the plants varies from plant to plant. Resveratrol is found effective in treating various health problems like heart disease, cancer, and imbalanced metabolism. It is a very effective anti-aging compound. It also acts against some bacterial and viral infections.




Resveratrol was discovered in the red wine and thus its major source is a natural product. The red grapes are considered to be the most efficient source of the resveratrol. Though there are few other sources of resveratrol that are present in nature like mulberries, peanut, cocoa, etc. The resveratrol is available in a varied amount in both natural as well as synthetic sources:

Natural Source (mg)

Synthetic source (mg/150 ml)

Red grapes (>0.24 & <1.25)

Red Wine (>0 & <2.78)

Cocoa (>0.28 & <0.46)

White wine (>0 & <0.17)

Peanuts (>0.01 & <0.26)

Peanut Butter (>0.04 & <0.13)


Synthetic source of resveratrol

There are few other synthetic sources for resveratrol that are available in the market as medicines and alcoholic compounds which are extracted from plants like Japanese knotweed, Cissus quadrangularis, Morus alba, etc. These are used by the traditional medicine practitioners for cardiac and bone diseases.

Synthetic sources of resveratrol that is consumed as supplements are easily available in the market. Most of the resveratrol supplements available in the market contain extract of the roots of Japanese knotweed (Polygonium cuspidatum). Red wine is the best dietary supplement for the resveratrol and it is recommended for long life.

Benefits of resveratrol

The resveratrol is an antioxidant compound that is found in a limited number of resources but recognized as one of the essential antioxidants. It has the property of increasing the lifespan of the living beings (no positive results in case of humans). Apart from this specific property, the resveratrol is found to have various health benefits and widely used by the medical professionals for treating various diseases. The following are some of the diseases that can be cured or prevented with the sufficient intake of resveratrol in diet:

  • Heart diseases

Resveratrol is effective in reducing the blood pressure and thus reduces the risk of heart diseases. It also prevents the endothelial layer of arteries and regulates the blood flow.

  • Cancer

According to the researches the resveratrol is found to have an effective role in the suppression of cancer as it minimizes the replication and enhances the death of these cancerous cells.

  • Alzheimer’s diseases

The resveratrol possesses the property to regulate the neurological system in humans. The resveratrol can pass through the mammalian blood-brain barrier and bind to the brain cells. The binding of resveratrol allows the glutamate uptake by the brain cells. The resveratrol reduces the risk of Alzheimer’s disease by preventing the aggregation of different proteins.

  • Diabetes

The insulin sensitivity is found to be affected by the resveratrol and thus have a role in glucose metabolism.

  • Obesity

The resveratrol enhances the apoptosis of fat cells present in the body. Thus, it can be used in the weight loss program. It inhibits the fatty acid synthase and lipoprotein lipase and enhances the process of fat metabolism.

  • Osteoporosis

The condition in which the bones start losing their cartilage layers is known as osteoporosis and resveratrol is effective in preventing the cartilage from degradation. Being an antioxidant, the resveratrol is capable of reducing the chance of inflammation and thus helps in preventing the bones from any kind of damage or infection.

  • Skin diseases and aging problem

Resveratrol is an antioxidant thus it helps in regulating the blood flow and helps in preventing the skin from different kind of problems like acne, etc. The resveratrol is an effective anti-aging compound as it regulates the blood flow and recovers the dead cells in the skin and removes wrinkles and prevents aging.

Side effects of resveratrol

Since the resveratrol is a natural compound thus it does not cause any side effect, but if the concentration of the supplement is higher than the tolerable amount for the body then it might cause some kind of health issues. The tolerable amount of resveratrol is 500 mg for healthy men and women. The recommended amount of resveratrol that a human body can bear is 5 g but that in some cases that can cause health problems like nausea, intestinal imbalance,

Precautions in dosage and consumption of resveratrol

Resveratrol sometimes inhibits the essential enzymes form the body and thus disturbs the body regulation like when it is combined with some of the medicines it can inhibit the blood clotting mechanism, disturb the blood pressure, etc. The pregnant ladies and lactating mothers should avoid the consumption of resveratrol. The dosage amount of resveratrol must be consulted with the health professional. It should be kept out of the reach of children.

FAQs: What people normally want to know about Resveratrol?

1. What is resveratrol?

Resveratrol is an antioxidant that helps in the recovery of the damaged cells in the body and it is known to increase the life in case of animals.

2. Is it a natural compound?

Yes, it is a natural compound present in the skin of red grapes. There are other natural sources also available like peanuts, cocoa, green grapes, mulberries, etc. Using these natural compounds synthetic supplements are produced.

3. Does it help in weight loss?

Yes, it helps in weight loss as it kills the fat cells present in the body.

4. Is it easily available in the market?

It is easily available in the market as natural as well as the synthetic source. Natural source available in the market include grapes, berries, cocoa, peanuts, etc. While products like peanut butter, red wine, sparkling wine, dark chocolate contain a high amount of resveratrol in them.

5. Are there any severe side effects of it?

No, there are no severe side effects of resveratrol but if it is taken in a higher amount than the recommended then it might cause problems like nausea and upset stomach.

6. What is more effective a natural source or synthetic supplement?

Natural sources are more beneficial than the supplements as they do not cause any kind of side effect. The reason is that the natural products have limited amount of resveratrol in them and thus does not cause any kind of side effect on human body.